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Additionally, participants were divided into low depression (score of 1 or 2 out of a possible score of four, as this is a core feature of MDD diagnosis) and high depression (score of 3 or greater out of a possible score of four)

A study by Clarkson et al

GLP-1 Agonist Use and Side Effects in the United States ResearchPublished Aug 6, 2025 GLP-1 agonists are a class of medications that are prescribed to manage blood sugar for those with type 2 diabetes and to treat obesity

Their conversation includes: How compounding pharmacies began compounding semaglutide

GLP-1 drugs work by promoting satiety, reducing food intake, and thus decreasing body weight and blood pressure

Importantly, no clinical trial participants stopped treatment due to hair loss, indicating the severity is generally mild to moderate