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only 1 of 19 patients with antibodies was taking concomitant methotrexate

This work is suspected of not respecting ethical and scientific standards and is, for some, the subject of ongoing legal proceedings. After years of criticism, including a 2023 letter raising serious concerns about methodological flaws in the study and an editorial conflict of interest (one of the co-authors was also editor-in-chief of the journal), the journal finally issued a lengthy retraction notice

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Given the cost of a brain MRI or PET scan, he focused on treatment rather than extra diagnostic testing

Available in 2ml and 10ml multi-dose variants