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What they found (summary): Amylin acts primarily in the area postrema , lesioning the area postrema abolishes the anorexigenic effect of amylin Acute vs chronic effect: acute, suppression of feeding

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For example, it should be considered that, compared to other endogenous orexigens, ghrelin has only modest effects on food intake in animal models

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Since then, over 100 peer-reviewed studies have been published examining its effects on tissue healing, inflammation, and organ protection