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However, the small sample-size, the short treatment period, the absence of control groups, the lack of liver biopsy evaluation after treatment are just some of the limitations of these studies

This disruption of DNA replication and repair and HSP protein refolding can trigger mitotic arrest and even apoptosis when injury is severe

Reduced level of glutamate has been reported in PFC of mice in different models of depression such as chronic unpredictable mild stress (CUMS) (66), chronic social defeat stress (CSDS) (112, 116), and chronic forced swim stress (CFSS) (122)

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