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Kaess BM, Pedley A, Massaro JM, Murabito J, Hoffmann U, Fox CS

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The medication operates as a dual-agonist, targeting both GLP-1 and GIP hormone pathways, which are instrumental in regulating appetite and insulin secretion

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Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product