More serious side effects include pancreatitis, changes in vision, low blood sugar (hypoglycemia), allergic reactions, acute kidney injury, and severe stomach problems
Sitagliptin, alogliptin, and linagliptin interact noncovalently with residues in the catalytic bag, then decompose unchanged as parent inhibitor molecules, and then interact freely with the enzyme again plus their inherent long half-life, resulting in sustained DPP4 inhibition, which is compatible with a once-daily dosing regimen [82,83]
Journal of Ethnopharmacology 194
more GLP-1 means healthier glucose levels
Management of type 2 diabetes: A handbook for general practice
Iliff JJ, Wang M, Liao Y, et al