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Trials still pending Two core obesity trials are still running: TRIUMPH-2 (obesity + type 2 diabetes) results expected later 2026 TRIUMPH-3 (obesity + established cardiovascular disease) results expected later 2026 A separate cardiovascular outcomes trial, TRIUMPH-Outcomes (~10,000 patients), is not required for the initial obesity NDA and wont report until 20282029

TLDR: go easy

In other words, glucagon agonism acts somewhat like a metabolic accelerator, burning more calories at rest

is growing at an alarming rate

Considering all factors combineda robust profile encompassing efficiency plus added health improvementsTirzepatide maintains its standing as a powerful option within the pharmaceutical choices available today