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The extent of these effects can vary greatly from woman to woman, as factors like starting weight, rate of weight loss, overall health, and any pre-existing menstrual irregularities will determine how weight loss might impact your cycle

A structured assessment can determine eligibility for existing licensed treatments, referral to a specialist weight management service (in line with NICE CG189), or enrolment in a clinical trial

Significant transformation often becomes apparent after 3-6 months of consistent treatment

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PMID: 27671545

MT-2 activates a broader range of melanocortin receptors including MC4R