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Compounded semaglutide contains the same active pharmaceutical ingredient as brand-name formulations and works through identical GLP-1 receptor mechanisms

Applying firm pressure, not just a tissue, but actual pressure, for 30 seconds after withdrawing the needle can reduce the risk of bruising by 70%

Twice-weekly dosing is not part of the TRIUMPH Phase 3 protocol

Because of this, the instructions for taking the pill are strict

The compounded formulations available through platforms like Wellorithm use active ingredients from the same drug class, prepared by licensed compounding pharmacies - but the compounded products themselves have not undergone the same FDA approval process as the brand-name versions

Rockville, MD: United States Pharmacopeial Convention, 2020