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Semaglutide GLP-1 is commonly used for its effectiveness in supporting healthy, sustainable weight loss

Whether this durability extends to two, three, or five years remains unknown pending longer-term follow-up studies

Thyroid concerns need monitoring

heart failure risk - An FDA warning (4/6/16) was added to saxagliptin regarding an increased risk of heart failure observed in two randomized trials (3.5% risk vs 2.8% for those taking placebo)

Sustained release strategy designed for lixisenatide delivery to synchronously treat diabetes and associated complications

The applications of GLP-1RAs extend far beyond diabetes management