The concomitant use of alcohol or central nervous system (CNS) depressant drugs (e.g., barbiturates, benzodiazepines, and sleep medications) with phentermine or topiramate may potentiate CNS depression or other centrally mediated effects of these agents
Dehydration from nausea and vomiting, electrolyte imbalances from reduced food intake, the physiological stress of rapid weight changes, interactions with caffeine, anxiety about taking a new medication, these are all factors that do not cleanly show up in trial adverse event tables but absolutely contribute to real-world palpitation experiences
Although oxidants can inactivate alpha-1 antitrypsin and other protective proteins, damage lung tissue, and increase mucus production, they also are essential for killing pathogens and resolving inflammation
Undoubtedly, they have become a popular option for shedding unwanted pounds
Similar changes can show up after gastric bypass surgery, extreme dieting, or any kind of dramatic weight loss
Tolerance or reduced response can happen
