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Ferrous iron (Fe 2+ ) catalyzes the Fenton reaction with hydrogen peroxide, generating hydroxyl radicals ( OH) that extract hydrogen atoms from bis-allylic carbons of polyunsaturated fatty acids (PUFAs)

Pasello et al reported that this agent effectively reversed cisplatin resistance in osteosarcoma, alluding toward potentially improved clinical outcomes when using a combination of NBDHEX and cisplatin

doi: 10.3389/fimmu.2024.1478374 144 HuangWYinHYangYJinLLuGDangZ

Chakraborty, C., Sharma, A

But when the liver becomes burdened by stress, alcohol, poor diet, or chronic inflammation, its ability to maintain these molecules weakens [7]

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