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A 2020 study in the European Journal of Pharmacology used lateral ankle ligament sectioning in rats to simulate Grade II sprains, administering BPC-157 intraperitoneally at 10 mcg/kg daily for 14 days

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Consistent with the phosphorylation of Met and the subsequent signalling proteins, the dimeric macrocycles are able to clearly mimic the functional role of hHGF and induce cellular responses in not only model cell lines but also various normal human cells (Figs 4, 5, 6 and Supplementary Figs 13 and 14)

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Transmigration of immune cells into tissues is facilitated by post-capillary venules

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Additionally, SPPEPS was demonstrated to significantly upregulate the expression of collagen XI1, a critical contributor of cartilage formation

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