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Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B et al (2017) Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

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As free radicals look for electrons to pair with, they can damage mitochondria, DNA, RNA, and proteins, which leads to oxidative stress

Similarly, Sp treatment resulted in maintained mitochondrial complex I activity which is found to be disrupted in PD patients and Parkinsonian models (Fig