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We use ESI-09 (a specific Epac inhibitor) to determine the contribution of Epac-dependent signaling pathway on protective effects of GLP-1R agonist

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This finding comes from two identical Phase 3 placebo-controlled clinical trials where female patients with HSDD were asked questions related to a Female Sexual Distress Scale-Desire/Arousal/Orgasm assessment

In PRO-ACT, the largest available clinical trial dataset for ALS, UA levels have been identified as one of the strongest predictors of ALS progression and survival [131]