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doi: 10.1371/journal.pone.0296733 85 ShuchengH.LiJ.LiuY.ChenX.JiangX

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Autophagy deficiency in neurons results in buildup of ubiquitinated proteins, dystrophy of neural terminals, impairments in synaptic transmission, and eventually, neurodegeneration observed in both neurodegenerative and neurodevelopmental disorders [245, 249, 250]