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Acquisition of stable inducible upregulation of nuclear factor-kappaB by tumor necrosis factor exposure confers increased radiation resistance without increased transformation in breast cancer cells

Receptor sensitisation: Some research suggests that alternating between different secretagogue mechanisms may prevent receptor downregulation compared to chronic stimulation of a single pathway

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The 5-oxoprolinase may regenerate glutamate from 5-oxoproline, but in an ATP-depleting futile cycle that eventually results in a progressive depletion of ATP and further accumulation of 5-oxoproline (Fig