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Cellular studies confirmed significant intracellular accumulation of LDH-NPs, leading to adequate clearance of intracellular bacteria [163]

The hydroxyl group of KA is oriented towards CuA with a distance of 3.3 , while the distance of the carbonyl group to CuA is 5.5

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When the MERRF gene is mutated, impairments of mitochondrial calcium uptake and ATP synthesis, which can trigger cellular energy deficiency-initiated neuronal excitotoxicity, are observed [67]

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