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A 2022 study in Diabetes, Obesity and Metabolism showed that NNMTi treatment combined with reduced-calorie diet "promoted dramatic whole-body adiposity and weight loss in diet-induced obese mice, rapidly normalizing" weight parameters
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Mendoza EN, Ciriolo MR, Ciccarone F
40,66 Leucine also positively regulates insulin secretion as it generates ATP via the Krebs cycle by allosterically stimulating glutamic dehydrogenase and producing alpha-ketoglutarate
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Volek JS, Kraemer WJ, Rubin MR, Gmez AL, Ratamess NA, Gaynor P (2002)
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