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This guidance is supported by cohort studies showing that adults with HBV and chronic liver disease have higher odds of cirrhosis and increased HCC risk ( Similar findings were reported in an Australian population study

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Efficacy and safety of setmelanotide, a melanocortin-4 receptor agonist, in patients with bardet-biedl syndrome and alstrm syndrome: A multicentre, randomised, double-blind, placebo-controlled, phase 3 trial with an open-label period