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TGF- also acts as a master regulator of fibrosis by stimulating fibroblast proliferation and differentiation into myofibroblasts via the SMAD2/3 signaling cascade

This is in contrast with the widely recognized hypothesis that cell death evolved as one of the cooperation mechanisms between cells in multicellular organisms (the multicellularity-cooperation hypothesis) [2]

10.1152/ajpendo.00403.2002 Am

Furthermore, we investigated whether VRK2 affects the transport of SLC7A11 by regulating ER-to-Golgi or Golgi-to-PM processes

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