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For many patients, peptides are better understood as supportive tools within a medically supervised wellness plan rather than direct bodybuilding drugs

de la Cuesta-Zuluaga J, Mueller NT, Corrales-Agudelo V, Velsquez-Meja EP, Carmona JA, Abad JM, Escobar JS

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We summarize mechanistic insights across cellular and molecular domains, critically appraise preclinical and clinical findings, and discuss translational challenges that include bioavailability and brain penetration, study heterogeneity, biomarker guided stratification, and pediatric safety