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K.ThurmanJ

concluded that ethanolic extract of Brazilian red propolis loaded with polymeric nanoparticles possesses anti-leishmanicidal capability (174, 218)

The other mechanism by which succinate supports tumorigenesis acts through the inhibition of hypoxia-inducible factor prolyl hydroxylase (PHD)

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Use for at least 30-60 days for best results

However, the concentration of these inhibitors required to trigger even partial hyphal inhibition was found to be above the established safety threshold of these drugs, which calls for further exploration to find anti-hyphal compounds with lower systemic toxicity [173]