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doi: 10.1159/000473879 18 HishikawaDShindouHKobayashiSNakanishiHTaguchiRShimizuT

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Bioinformatics analyses using the Broad Institute Connectivity Map identified GHK-Cu as a modulator of more than 4,000 human genes, with the expression signature appearing to reverse patterns associated with aging and age-related disease (PMID: 25904764)

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Of all the respiratory diseases included, it was pulmonary emphysema that displayed the strongest association with risk of LC (OR =2.87