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The probe performs similarly to non-modified SNAP-Lumi4-Tb for GLP-1R labelling, measurements of fluorescent GLP-1R agonist binding and for internalisation by DERET (Supplementary Figure 2B, 2C, 2D)

[Google Scholar] 28.Choudhary R, Bowser TJ, Weckler P, Maness NO, McGlynn W

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The pathogenic potential of excess body fat is indeed conditioned on its visceral extent and dysfunction, the latter defined by inflammation, insulin resistance, and ectopic fat deposition [19]

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This results in them eating less leading to quick and often quite dramatic weight loss