Back Edwards, K, Li, X, Linvay, I (1 April 2023) 'Clinical and safety outcomes with GLP-1 receptor agonists and SGLT2 inhibitors in type 1 diabetes: A real-world study', The Journal of Clinical Endocrinology & Metabolism , 108/ 4, 92030
Whether that closes the gap to retatrutide depends on the actual data, but the strategic logic adding a second mechanism to semaglutide because semaglutide alone can no longer compete on efficacy is now obvious
Research is ongoing, and results are not yet definitive
Whilst serious complications from a single early dose are uncommon, your safety is paramount, and healthcare professionals can provide appropriate assessment and management tailored to your situation
Parker CH, Slattery C, Brennan DJ, le Roux CW
Digestion, peristalsis, immune system function, and healing are all put on hold when the SNS is engaged, and hormones related to SNS activation are released