Popular Brands Hospira (Pfizer) Cyanocobalamin Injection American Regent Cyanocobalamin Fresenius Kabi Cyanocobalamin Sandoz Cyanocobalamin Teva Cyanocobalamin Strengths 1000 mcg/mL (standard adult & clinical dose) 500 mcg/mL (pediatric or dose-adjusted therapy) 2000 mcg/mL (high-strength for severe deficiency) Typical regimen: 1000 mcg IM weekly, then monthly maintenance (per healthcare providers direction)
Pickart & Margolina 2014 Chelates free copper, reduces oxidative damage, and upregulates superoxide dismutase the body's primary antioxidant enzyme
Its mechanism of action involves delaying stomach emptying and slowing intestinal motility, leading to prolonged satiety
In brain metastases, for example, gap junctions formed between tumor cells and resident astrocytes create direct channels for the efflux of chemotherapeutics and the exchange of pro-survival signals, thereby creating a formidable sanctuary for resistance [127]
Post parturient paresis, paralysis of limbs
Barton L, Murphy DV, Butterbach-Bahl K