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Yet we are still unsure whether higher levels of IGF-1 in old age is good for our health

Conflicts of Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

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Mechanisms of action Tirzepatide is a dual GLP-1/GIP receptor agonist that occupies GLP-1 and GIP receptors simultaneously to improve metabolic health

Insulin can be initially hydrolyzed by an insulin protease followed by the action of plasma-membrane-associated or lysosomal proteases