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Conceptualization: [Yanni Yao, Siyan Chen, and Meng Sun]

In laboratory and pre-clinical research settings, native GLP-1 serves as the primary pharmacological reference standard for studying GLP-1 receptor binding, activation, and downstream signalling as well as the broader incretin axis and its connections to pancreatic -cell biology, appetite regulation, gastric motility, cardiovascular function, and neuroprotection

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