Taking into account that SGLT-2i and GLP-1RA are recommended as therapeutic alternatives by many clinical guidelines, usually as second-line treatments after first-line metformin, new users of SGLT-2i appear to be a suitable active comparator group
She took up running half-marathons, but at that weight, it was painful
This is why it is important to understand what additional weight management efforts patients pursue in real-world settings after discontinuing semaglutide or tirzepatide, and whether long-term weight changes after discontinuation follow the patterns reported in randomized clinical trials. Hamlet Gasoyan, DS, PhD, MPH According to the researchers, a potential reason for the difference may be that people often continue their treatment journey in other ways
And once thats gone, its really difficult to maintain any sort of behaviors that were helping you to keep the weight off, she says
At the time, the medication was covered by her health insurance
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