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While these medications have a relatively low intrinsic risk of causing dangerously low blood sugar when used alone, the risk increases significantly when combined with insulin or sulfonylureas

Dowlatshahi 2013

Respondents were between 25 and 70 years and reported living with diabetes between 1 and 20 years

Cimetidine a promising radio-protective agent through modulating Bax/Bcl2 ratio: an in vivo study in male rats

Rivera-Iiguez, Ingrid, et al

Other factors and medications can layer on top of the medication effects, creating a compounding fatigue picture that is difficult to untangle without systematic thinking