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Similarly, those who have undergone bariatric surgery or bowel resection may have compromised absorption capacity

In an unbound state, the AR complexes with heat-shock, chaperone and co-chaperone proteins (such as HSP90, HSP70, and p23), which helps to maintain the apo state of the AR in a state competent to bind ligand (Figure 1A) 73

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The finding that younger people with COVID-19 also are glutathione deficient and have elevated oxidative stress and oxidant damage is really surprising, because we do not normally see these defects in younger age groups