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The Long R3 modification prevents it from binding to IGF-binding proteins, allowing it to remain active in the body for a longer duration

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Novo Nordisks semaglutidemarketed as Ozempic for type 2 diabetes (T2D) and Wegovy for weight losssaw the biggest jump in T1D uptake, jumping from 0.2% in 2018 to 4.4% in 2023