Phase 3 clinical trials into survodutide, a new GLP-1, showed it has the potential to combat NASH, one of the complications of NAFLD, with significant improvements seen in 83.0% of patients
But the states two biggest insurers, Blue Cross Blue Shield of Massachusetts and Point32Health, the owner of Harvard Pilgrim and Tufts Health Plan, are ending coverage of GLP-1 drugs for weight loss next year because of spiraling costs
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overall serious adverse events were uncommon but must be reviewed in full text for details OASIS-4 Trial (25 mg) x STEP Trial (2.4 mg) The STEP trials that formed the evidence base for the once-weekly subcutaneous semaglutide 2.4 mg (Wegovy) showed mean weight reductions in the range of around 14.9% to 17% at 68 weeks in adults without diabetes
While this hasnt been strongly replicated in humans, it could play a supporting role in long-term weight maintenance when combined with healthy habits
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