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The lethal dose in humans would be approximately 21,000mg for a 70kg person, making the 1-3mg daily doses used in typical protocols extremely safe from a toxicity standpoint
Adjudication engines treat D64.x as the "other and unspecified anemias" family and reject infusion claims that require a nutritional anemia code
Equally important, all included studies reported positive findings, with no clearly negative or null results identified
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This can provide higher accuracy, specificity, and sensitivity