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Finan, B

Adjusts every dose

First-line treatment typically involves: Methotrexate the most commonly prescribed conventional synthetic DMARD Sulfasalazine or hydroxychloroquine alternative or combination options Leflunomide for patients who cannot tolerate methotrexate These medications are usually combined with short-term corticosteroids (such as prednisolone) to provide rapid symptom relief whilst DMARDs take effect, which can take several weeks to months

8 BMI: At baseline, mean BMI was 38.6 (4.7) kg/m 2 in the placebo arm and 37.6 (7.9) kg/m 2 in the exenatide arm

Diabetes Endocrinol

They have not gone through the strict safety, dosage, or absorption testing required for FDA-approved drugs