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This is because both compounds affect gastrointestinal motility and appetite through their respective mechanisms, and layering them too aggressively creates compounding GI effects that can derail compliance

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specifically, the fleeting existence of radical species and the rapid rate at which redox cycling can generate ROS, causing oxidative stress 5,7,28

Once reconstituted, it should be refrigerated and used within 2448 hours to maintain stability

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