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Consistent complaints about poor communication, unsafe products, or unprofessional behavior are warning signs

In addition to inducing HF by promoting atherosclerotic progression, elevated plasma TMAO levels may accelerate myocardial hypertrophy, exacerbate mitochondrial dysfunction, and induce transverse-tubule (T-tubule) remodeling in cardiomyocytes (93)

However, there are no large prospective randomised clinical trials (RCTs) that demonstrate CV risk reduction with lowering of serum uric acid levels [79, 80]

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While use of the GLP-1 medications has skyrocketed, evidence on their long-term impact is still being assessed