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The temporal association between drug administration and symptom onset, along with the exclusion of other potential causessuch as trauma, current infections, electrolyte disturbances, and drug abusestrongly supports this link

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Beyond nutritional approach, many drugs, including Metformin [19], Sibutramine, and Rimonabant [20, 21], Orlistat and Lorcaserin, and Naltrexone-Bupropion [22] have been used over the years in patients with PWS

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It is essential to select appropriate exercises tailored to individual tolerance levels under medical supervision, as this can contribute to the overall well-being of patients

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