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Footnotes Updates in response to a review critique including some clarifications to terms

The experimental and surgical procedures for the large animal studies were approved by the Animal Ethics Committee of the Shanghai Jiaotong University School of Medicine and were carried out in compliance with the regulations and guidelines of the Shanghai Jiao Tong University Institutional Animal Care and with the AAALAC and IACUC guidelines

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There is limited information regarding the tertiary structures of OATPs, although more recent studies are beginning to address this aspect