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Periodic treatment breaks are commonly recommended to prevent receptor adaptation and ensure continued responsiveness

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BPC-157 has been shown in research to alleviate leaky gut, IBS, intestinal cramps, and Crohns disease by acting on many pathways in the digestive tract

This 48-week, phase 2, dose-ranging trial enrolled 338 adults with obesity (BMI 30) but without diabetes, randomising participants to placebo or one of four retatrutide doses: 1mg, 4mg, 8mg, or 12mg administered subcutaneously once weekly