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In fact, some different thiol-masking agents are routinely used to measure GSH and GSSG, such as alkylating agents (iodoacetic acid, NEM), 2-VP, 5-methyl methanethiosulfonate, monobromobimane [19]

When used together, these medications may offer a synergistic effect on weight loss efforts

Plant polyphenols, such as resveratrol found in grapes and red wine, can activate key regulatory pathways involving sirtuins and the peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1), which promote the expression of genes involved in mitochondrial function 15,16,17

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DeLeve LD, Kaplowitz N (1991) Glutathione metabolism and its role in hepatotoxicity

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