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The SOD gene family members are located on different chromosomes, SOD1 on 21q22.11, SOD2 on 6q25.3, and SOD3 on 4p15.3p15.1 are coding for the intracellular CuZn-SOD (SOD1), mitochondrial Mn-SOD (SOD2), and extracellular EC-SOD (SOD3) enzymes, respectively [30,31]

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Front Neurosci (2010) 4:52.10.3389/fnins.2010.00052 19 FryeREHuffmanLCElliottGR