do we know the long term effects of glp 1 New Research on GLP-1s & Bone Health 🦴 ​A new large-scale study has raised questions about long-term GLP-1 receptor agonists (like Ozempic and Wegovy). While these medications are revolutionary GLP-1RA Essentials in Gastroenterology: Side

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Abbreviations KOA: Knee osteoarthritis LPS: Lipopolysaccharide FLS: Fibroblast-like synoviocytes AMPK: AMP-activated protein kinase CPT1: Carnitine palmitoyltransferase 1 Cyc: Cytochrome c ACLT: Anterior cruciate ligament transection NSAIDs: Non-steroidal anti-inflammatory drugs CoA: Coenzyme A SOD: Superoxide dismutase MDA: Malonaldehyde ATP: Adenosine-triphosphate ROS: Reactive oxygen species CCK-8: Cell counting kit-8 DMEM: Dulbeccos modified Eagles medium IL-1: Interleukin-1 siRNA: Small interfering RNA References Sharma L

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The statistical analysis was performed by one-way ANOVA and the comparison between different groups were performed

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