1 The discovery of GLP-1 The journey began with Habener and Mojsovs identification of the physiological roles of GLP-1, a hormone initially discovered as an incretin, which is released by the gut (Drucker et al 1986) (Fig
Pi-Sunyer X, Astrup A, Fujioka K, Greenway F, Halpern A, Krempf M, Lau DCW, le Roux CW, Violante Ortiz R, Jensen CB, et al
For example, the Diabetes Prevention Program is known to reduce risk of progression to diabetes and is covered by major payers, but has not been meaningfully scaled due to regulatory and implementation barriers
Comparison: Injectable Wegovy (Real World): ~15.4% weight loss
Some of these strategies can help bring about immediate cost savings, but they all work to improve quality and reduce costs over time
That is why the cash-pay manufacturer programs (NovoCare and LillyDirect) matter so much for uninsured or underinsured patients