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Lysine and methionine are limiting amino acid, which means they are most likely to be deficient relative to the horses requirements

Higher doses can upset your stomach, so it's best to start with smaller amounts

You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase

2008) investigated the pharmacokinetics of 2, 5, 10, and 15 g of citrulline within eight healthy volunteers and demonstrated that larger doses could be more appropriate

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Lancet Neurol 16:465477