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The therapeutic potential of vitamin D in PCOS is largely attributed to its systemic antioxidant and anti-inflammatory properties (101)

We designed an optimized LNP by replacing cholesterol with equal amount of -sitosterol, which was defined as the X% LNP (X% is the ratio of -sitosterol to LNP)

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Interestingly, bioinformatic analyses conducted on bulk tissue data obtained from healthy human brain tissue donors revealed that endothelial cells and microglia were the predominant senescent cell types, driven by CDKN1A/p21WAF1/CIP1 (42) revealing potential differences in senescent cell types between healthy and diseased states