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If that molecule happens to be DNA, the resulting mutation can lead to cancer

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Findings from other models of CNS degeneration, suggesting that normalization of the NADH/NAD + ratio promotes viability, support that this ratio (which is also a proxy for LPR) represents the connection between metabolic and inflammatory processes after injury [68, 69]

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Schell TD, Mylin LM, Georgoff I, Teresky AK, Levine AJ, Tevethia SS