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Researchers have reported that GHK influences the activity of a strikingly large number of genes in lab models, and that our natural levels drop meaningfully with age (from roughly 200 ng/mL in plasma around age 20 to about 80 ng/mL by age 60)

However, only high-frequency activity induces tissue plasminogen activator secretion, resulting in the conversion of pro- to mature BDNF (13)

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