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It doesnt cure aging (nothing does), but it appears to modulate several pathways that otherwise accelerate it

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In hepatic insulin resistance, normal tyrosine phosphorylation of IR and IRS is compromised, diminishing PI3K activity associated with IRS

This risk is increased in people with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)

This only happens in the presence of B12 and when theres deficiency, homocysteine levels build up

383 TFEB and Beclin-1 activators TFEB, a master regulator of lysosomal biogenesis and autophagy, has emerged as a particularly attractive target